Grande and Minaj performed "Side To Side" together on November 20, 2016, at the American Music Awards where Minaj also performed "Do You Mind" with DJ Khaled; They had previously performed the song on August 28, 2016 at the 2016 MTV Video Music Awards.
Grande posted a picture of the cover for Minaj's single "Regret In Your Tears" with the caption '♡ ♡ ♡ @nickiminaj ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡'
Grande and Minaj call each other sisters.
When paparazzi asked Minaj to comment on the events in Manchester, she said "Ariana is my sister, I love her, and I love the people of the UK, and I'm devastated by the news; it's heartbreaking".
On April 12, 2018, Grande posted a Instagram story listening to Minaj's song "Chun-Li" and wrote "Missed Ya Sis".
On May 12, 2018, Grande tweeted "i love my big sis @nickiminaj so fuckin much" and "remember when u called me at 5am and said get ur ass up n come to the stu btch and i propelled myself out the door at the speed of light wearing slippers that later got soaked in rain and we had the best morning of my life i do" confirming that they were in the studio together.
On May 12, 2018, Grande posted a boomerang of her in the studio with Minaj.
On May 27, 2018, Grande posted a 21-second snippet of "The Light Is Coming", the pair's most recent collaboration.
On June 9, 2018, Grande and Minaj posted a video on Twitter of both saying "eat my ass".
Minaj mentions Grande and her song "Thank U, Next" on her 2019 freestyle "Bust Down Barbiana" with the lyric "Killin' everybody beat, thank u, next, Ariana".
On April 14, 2019, while Grande headlined Coachella Valley Music and Arts Festival weekend 1, Minaj was one of the guest performers, they performed "Side To Side" and "Bang Bang".